APRT (NM_000485) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 19.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000476 |
| Locus ID | 353 |
| UniProt ID | P07741 |
| Cytogenetics | 16q24.3 |
| RefSeq Size | 807 |
| RefSeq ORF | 540 |
| Synonyms | AMP; APRTD |
| Summary | Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "APRT" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH316874 | APRT MS Standard C13 and N15-labeled recombinant protein (NP_000476) | 10 ug |
$3,360.00
|
|
| LC422236 | Lyophilized APRT HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424695 | Lyophilized APRT HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY422236 | Transient overexpression lysate of adenine phosphoribosyltransferase (APRT), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424695 | Transient overexpression lysate of adenine phosphoribosyltransferase (APRT), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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