MAP2 (NM_002374) Human Recombinant Protein

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SKU
TP316775
Recombinant protein of human microtubule-associated protein 2 (MAP2), transcript variant 1, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>Peptide sequence encoded by RC216775
Blue=ORF Red=Cloning site Green=Tag(s)

MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSN
TKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPP
PSPASEQTVTVEEDLLTASKMEFHDQQELTPSTAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTY
PDKKDMQGTEEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKD
EWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGSFTLPLDVMKNEIVTETSPFAPAFL
QPDDKKSLQQTSGPATAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEA
INQETVQQRDTFTPSGQEPILTEKETELKLEEKTTISDKEAVPKESKPPKPADEEIGIIQTSTEHTFSE
QKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRVDDKDKIEGVGA
ATSAELDMPFYEDKSGMSKYFETSALKEEATKSIEPGSDYYELSDTRESVHESIDTMSPMHKNGDKEFQ
TGKESQPSPPAQEAGYSTLAQSYPSDLPEEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLG
GRSAIEQRSMSINLPMSCLDSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDDYLPATTPALEKAPCF
PVESKEEEQIEKVKATGEESTQAEISCESPFLAKDFYKNGTVMAPDLPEMLDLAGTRSRLASVSADAEV
ARRKSVPSETVVEDSRTGLPPVTDENHVIVKTDSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFY
EGTDDKVRRDLATDLSLIEVKLAAAGRVKDEFSVDKEASAHISGDKSGLSKEFDQEKKANDRLDTVLEK
SEEHADSKEHAKKTEEAGDEIETFGLGVTYEQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPSKKVE
QGLDFAVQGQLDVKISDFGQMASGLNIDDRRATELKLEATQDMTPSSKAPQEADAFMGVESGHMKEGTK
VSETEVKEKVAKPDLVHQEAVDKEESYESSGEHESLTMESLKADEGKKETSPESSLIQDEIAVKLSVEI
PCPPAVSEADLATDERADVQMEFIQGPKEESKETPDISITPSDVAEPLHETIVSEPAEIQSEEEEIEAQ
GEYDKLLFRSDTLQITDLGVSGAREEFVETCPSEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRF
AALEQPEVERRPSPHDEEEFEVEEAAEAQAEPKDGSPEAPASPEREEVALSEYKTETYDDYKDETTIDD
SIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRISTPERKVAKKE
PSTVSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPS
VFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGK
SGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT
PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKI
ESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRL
SNVSSSGSINLLESPQLATLAEDVTAALAKQGL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV

Recombinant protein using RC216775 also available, TP316775
Tag C-Myc/DDK
Predicted MW 199.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002365
Locus ID 4133
UniProt ID P11137
Cytogenetics 2q34
RefSeq Size 6534
RefSeq ORF 5481
Synonyms MAP-2; MAP2A; MAP2B; MAP2C
Summary This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. provided by RefSeq, Jan 2010
Protein Categories Intracellular Proteins
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS
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Other "MAP2" proteins (11)
SKU Description Size Price
PH316775 MAP2 MS Standard C13 and N15-labeled recombinant protein (NP_002365) 10 ug
$3,360.00
PH321637 MAP2 MS Standard C13 and N15-labeled recombinant protein (NP_114033) 10 ug
$3,360.00
LC410495 Lyophilized MAP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC410496 Lyophilized MAP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419369 Lyophilized MAP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422067 Lyophilized MAP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410495 Transient overexpression lysate of microtubule-associated protein 2 (MAP2), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY410496 Transient overexpression lysate of microtubule-associated protein 2 (MAP2), transcript variant 4 (as WB positive control) 100 ug
$665.00
LY419369 Transient overexpression lysate of microtubule-associated protein 2 (MAP2), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY422067 Transient overexpression lysate of microtubule-associated protein 2 (MAP2), transcript variant 5 (as WB positive control) 100 ug
$665.00
TP321637 Recombinant protein of human microtubule-associated protein 2 (MAP2), transcript variant 2, 20 µg 20 ug
$867.00

file-alt Citations

CSF levels of the somatodendritic protein MAP2 are increased in ALS and predict shorter survival
Verde, Vávra, Dorst et al
J Neurol Neurosurg Psychiatry (2025)
Cited by 3
AI Summary: OriGene’s recombinant full-length MAP2 protein (catalog number TP316775) was used to prepare calibration standards for measuring MAP2 levels in cerebrospinal fluid, enabling quantitative analysis of this biomarker in ALS patients.
Snippet: prepared at concentrations of 5000, 2500, 1250, 625, 313, 156 and 104 pg/mL in 0.5% human serum (in PBS) using recombinant full-length MAP2 (TP316775, Origene)
Sex-Based Differences in Plasma Autoantibodies to Central Nervous System Proteins in Gulf War Veterans versus Healthy and Symptomatic Controls
Abou-Donia, Krengel, Lapadula et al
Brain Sci (2021) 11 (2) DOI: 10.3390/brainsci11020148
Cited by 9
AI Summary: OriGene contributed to this study by providing the human recombinant Microtubule-Associated Protein 2 (MAP-2, Cat. #TP316775), which was used as an antigen to measure plasma autoantibody levels in Gulf War veterans and control groups.
Snippet: …The sources of protein were also described previously [19]: Tubulin (human recombinant, Prospec Cat. # PRO-982), Microtubule-Associated Protein 2 (MAP-2, human recombinant, Origene, Cat. #TP316775 Cached;- 33]). 2.2. … The sources of protein were also described previously [19]: Tubulin (human recombinant, Prospec Cat. # PRO-982), Microtubule-Associated Protein 2 (MAP-2, human recombinant, Origene, Cat. #TP316775 Cached
Using Plasma Autoantibodies of Central Nervous System Proteins to Distinguish Veterans with Gulf War Illness from Healthy and Symptomatic Controls
Abou-Donia, Lapadula, Krengel et al
Brain sciences (2020) 10 (9) DOI: 10.3390/brainsci10090610
Cited by 20
AI Summary: In this study, the OriGene product Microtubule-Associated Protein 2 (MAP-2, human recombinant, Cat. #TP316775) was used as an antigen to detect plasma autoantibodies, contributing to the identification of objective biomarkers for distinguishing Gulf War Illness from control groups.
Snippet: PRO-982, ProSpec-Tany TechnoGene Ltd., East Brunswick, NJ, USA), Microtubule-Associated Protein 2 (MAP-2, human recombinant, Cat. #TP316775, OriGene, Rockville, MD, USA), Tau-381 (human recombinant, Cat. #AG952 Cached
Showing 1-3 of 3 papers.
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