VAV2 (NM_003371) Human Recombinant Protein

CAT#: TP316175

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Recombinant protein of human vav 2 guanine nucleotide exchange factor (VAV2), transcript variant 2


 Product Datasheet for 'TP316175'

 Cited in 1 publication.

  View other "VAV2" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human vav 2 guanine nucleotide exchange factor (VAV2), transcript variant 2
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 96.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity In vitro kinase assay substrate (PMID: 28712859)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003362
Locus ID 7410
Refseq Size 4707
Cytogenetics 9q34.2
Refseq ORF 2517
Synonyms VAV-2
Summary VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway

Citations (1)

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Other Versions

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