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MACROD2 (NM_001033087) Human Recombinant Protein

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SKU
TP315636M
Recombinant protein of human MACRO domain containing 2 (MACROD2), transcript variant 2, 100 µg
Size:
100 ug 20 ug 1 mg
  $2,950.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC215636 protein sequence
Red=Cloning site Green=Tags(s)

MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFA
KDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTE
DQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRN
GTK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 23.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001028259
Locus ID 140733
UniProt ID A1Z1Q3
Cytogenetics 20p12.1
RefSeq Size 4425
RefSeq ORF 639
Synonyms C2orf133; C20orf133
Summary The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. provided by RefSeq, May 2017
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

Sindbis Macrodomain Poly-ADP-Ribose Hydrolase Activity Is Important for Viral RNA Synthesis
Aguilar, Paniccia, Adura et al
J Virol (2022) 96 (7), e0151621 DOI: 10.1128/jvi.01516-21
Cited by 12
AI Summary: OriGene’s MacroD2 protein (cat no. TP315636) was used as a positive control for mono-ADP-ribosylhydrolase (mono-ARH) activity in this study, helping to assess the enzymatic specificity of viral macrodomains.
Snippet: (0.5 μM macrodomain final concentration) and allowed to incubate at 37°C for 1 h. acroD2" style="font-weight: bold;">MacroD2 (Origene cat no. TP315636) and TARG1 (Cusabio Technology LLC CSB-EP896727HU) were included as positive controls for mono-ARH activity. After the reaction was complete 10 μL 4xLDS NuPAGE buffer was added to each sample and 5 μL 10x
Showing 1-1 of 1 papers.
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