LCE3B (NM_178433) Human Recombinant Protein
CAT#: TP315298
Recombinant protein of human late cornified envelope 3B (LCE3B), 20 µg
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC215298 representing NM_178433
Red=Cloning site Green=Tags(s) MSCQQNQQQCQPLPKCPSPKCPPKSSAQCLPPASSCCAPRPGCCGGPSSEGGCCLSHHRCCRSHRCRRQS SNSCDRGSGQQDGASDCGYGSGGCC TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 9.6 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_848520 |
Locus ID | 353143 |
UniProt ID | Q5TA77 |
Cytogenetics | 1q21.3 |
Refseq Size | 288 |
Refseq ORF | 285 |
Synonyms | LEP14 |
Summary | A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035).[UniProtKB/Swiss-Prot Function] |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC405957 | LCE3B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY405957 | Transient overexpression lysate of late cornified envelope 3B (LCE3B) |
USD 436.00 |
|
PH315298 | LCE3B MS Standard C13 and N15-labeled recombinant protein (NP_848520) |
USD 3,255.00 |
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