ERC1 (NM_178040) Human Recombinant Protein
SKU
TP313864
Purified recombinant protein of Homo sapiens ELKS/RAB6-interacting/CAST family member 1 (ERC1), transcript variant epsilon, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 127.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_829884 |
| Locus ID | 23085 |
| UniProt ID | Q8IUD2 |
| Cytogenetics | 12p13.33 |
| RefSeq Size | 6893 |
| RefSeq ORF | 3348 |
| Synonyms | Cast2; ELKS; ERC-1; RAB6IP2 |
| Summary | The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ERC1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH313864 | ERC1 MS Standard C13 and N15-labeled recombinant protein (NP_829884) | 10 ug |
$3,360.00
|
|
| LC406029 | Lyophilized ERC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY406029 | Transient overexpression lysate of ELKS/RAB6-interacting/CAST family member 1 (ERC1), transcript variant epsilon (as WB positive control) | 100 ug |
$665.00
|
|
Citations
Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons
Negrete-Hurtado, Overhoff, Bera et al
Nat Commun (2020) 11 (1), 1535 DOI: 10.1038/s41467-020-15287-9
Negrete-Hurtado, Overhoff, Bera et al
Nat Commun (2020) 11 (1), 1535 DOI: 10.1038/s41467-020-15287-9
Cited by 39
AI Summary: OriGene’s purified recombinant MYC/DDK tagged human ERC1 protein (CAT#: TP313864) was used in protein interaction assays to investigate the regulation of microtubule dynamics by autophagy-related proteins in neurons.
Snippet: ptoethanol, Roth). The His6-LC3 containing fractions were pooled, shock-frozen in liquid nitrogen and stored at −80 °C. Purified recombinant MYC/DDK tagged human ERC1 protein was purchased from (OriGene CAT#: TP313864). For the assay 2 µg of His6-LC3B was mixed with 1 µg of MYC/DDK-ERC1 in reaction buffer (50 mM Tris, pH 7.6, 500 mM NaCl, 5 mM MgCl2, 2 mM β-mercaptoethanol, 10%
Showing 1-1 of 1 papers.
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