PPM1G (NM_177983) Human Recombinant Protein

CAT#: TP313685

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Recombinant protein of human protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), transcript variant 1


 Product Datasheet for 'TP313685'

 Cited in 1 publication.

  View other "PPM1G" proteins (10)

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USD 748.00


Availability*
In Stock

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC213685. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 59.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity In vitro phosphatase assay (PMID: 25658463)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_817092
Locus ID 5496
Refseq Size 2302
Cytogenetics 2p23.3
Refseq ORF 1638
Synonyms PP2CG; PP2CGAMMA; PPP2CG
Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
Protein Families Druggable Genome, Phosphatase

Citations (1)

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