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PTPN18 (NM_014369) Human Recombinant Protein

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SKU
TP313476
Recombinant protein of human protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Recombinant protein was produced with TrueORF clone, RC213476. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 50.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055184
Locus ID 26469
UniProt ID Q99952
Cytogenetics 2q21.1
RefSeq Size 2837
RefSeq ORF 1380
Synonyms BDP1; PTP-HSCF
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2008
Protein Categories Growth Factors, Intracellular Proteins
Protein Families Druggable Genome, Phosphatase
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Other "PTPN18" proteins (5)
SKU Description Size Price
PH313476 PTPN18 MS Standard C13 and N15-labeled recombinant protein (NP_055184) 10 ug
$3,360.00
LC415333 Lyophilized PTPN18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428059 Lyophilized PTPN18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415333 Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY428059 Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 2 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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