PTPN18 (NM_014369) Human Mass Spec Standard

SKU
PH313476
PTPN18 MS Standard C13 and N15-labeled recombinant protein (NP_055184)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213476
Predicted MW 50.3 kDa
Protein Sequence
Protein Sequence
RC213476
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055184
RefSeq Size 2837
RefSeq ORF 1380
Synonyms BDP1; PTP-HSCF
Locus ID 26469
UniProt ID Q99952
Cytogenetics 2q21.1
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2008
Protein Families Druggable Genome, Phosphatase
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Other "PTPN18" proteins (5)
SKU Description Size Price
LC415333 Lyophilized PTPN18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428059 Lyophilized PTPN18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415333 Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY428059 Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP313476 Recombinant protein of human protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), transcript variant 1, 20 µg 20 ug
$737.00

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