Bcl2 Binding component 3 (BBC3) (NM_014417) Human Recombinant Protein
SKU
TP313203
Recombinant protein of human BCL2 binding component 3 (BBC3), transcript variant 4, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 20.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055232 |
| Locus ID | 27113 |
| UniProt ID | Q9BXH1 |
| Cytogenetics | 19q13.32 |
| RefSeq Size | 1840 |
| RefSeq ORF | 579 |
| Synonyms | JFY-1; JFY1; PUMA |
| Summary | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2011 |
| Protein Families | Druggable Genome |
| Protein Pathways | Huntington's disease, p53 signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Bcl2 Binding component 3" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH313203 | BBC3 MS Standard C13 and N15-labeled recombinant protein (NP_055232) | 10 ug |
$3,360.00
|
|
| PH325345 | BBC3 MS Standard C13 and N15-labeled recombinant protein (NP_001120712) | 10 ug |
$3,360.00
|
|
| LC402330 | Lyophilized BBC3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426734 | Lyophilized BBC3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402330 | Transient overexpression lysate of BCL2 binding component 3 (BBC3), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426734 | Transient overexpression lysate of BCL2 binding component 3 (BBC3), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP325345 | Recombinant protein of human BCL2 binding component 3 (BBC3), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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