SOX6 (NM_033326) Human Recombinant Protein

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SKU
TP312046
Recombinant protein of human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 2, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC212046 protein sequence
Red=Cloning site Green=Tags(s)

MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVSTIQQDADWD
SVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLE
EMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHD
EQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLA
AAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINQRLKGLSDRFGRNL
DTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEA
AAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALF
GDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNED
GKLGPGVIDLTRPEDAEGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN
ISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQE
MRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLA
GNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 89.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_201583
Locus ID 55553
UniProt ID P35712
Cytogenetics 11p15.2
RefSeq Size 8865
RefSeq ORF 2424
Synonyms HSSOX6; SOXD; TOLCAS
Summary This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.provided by RefSeq, Mar 2009
Protein Categories Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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Other "SOX6" proteins (5)
SKU Description Size Price
PH311525 SOX6 MS Standard C13 and N15-labeled recombinant protein (NP_059978) 10 ug
$3,360.00
PH312046 SOX6 MS Standard C13 and N15-labeled recombinant protein (NP_201583) 10 ug
$3,360.00
LC403243 Lyophilized SOX6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403243 Transient overexpression lysate of SRY (sex determining region Y)-box 6 (SOX6), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP311525 Recombinant protein of human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1, 20 µg 20 ug
$867.00

file-alt Citations

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis
Leow, Poschmann, Too et al
Development (2016)
Cited by 56
AI Summary: OriGene products, specifically the GFP-tagged plasmids containing the mouse Sox6 gene (MG227129) and the human SOX6 gene (RG211525), were used in this study to investigate the role of SOX6 in promoting adipogenesis and its contribution to the developmental origins of obesity.
Snippet: with 2.5 µg GFP-tagged plasmid containing the mouse Sox6 gene (MG227129;Origene Technologies) in 6cm dishes. ... pTK–Renilla luciferase (Promega, E2241) and 1500ng GFP-tagged plasmid containing the human SOX6 gene (Origene Technologies, RG211525 ... Cite SaveSaving
Showing 1-1 of 1 papers.
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