COP (CARD16) (NM_052889) Human Recombinant Protein
SKU
TP311537
Recombinant protein of human caspase recruitment domain family, member 16 (CARD16), transcript variant 2, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 10.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_443121 |
| Locus ID | 114769 |
| UniProt ID | Q5EG05 |
| Cytogenetics | 11q22.3 |
| RefSeq Size | 758 |
| RefSeq ORF | 303 |
| Synonyms | COP; COP1; PSEUDO-ICE |
| Summary | Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "COP" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH311537 | CARD16 MS Standard C13 and N15-labeled recombinant protein (NP_443121) | 10 ug |
$3,360.00
|
|
| LC409399 | Lyophilized CARD16 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422744 | Lyophilized CARD16 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409399 | Transient overexpression lysate of caspase recruitment domain family, member 16 (CARD16), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422744 | Transient overexpression lysate of caspase recruitment domain family, member 16 (CARD16), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP760353 | Purified recombinant protein of Human caspase recruitment domain family, member 16 (CARD16), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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