PF4 (NM_002619) Human Recombinant Protein
Specifications
Product Data | |
Description | Recombinant protein of human platelet factor 4 (PF4) |
Species | Human |
Expression Host | HEK293T |
Tag | C-Myc/DDK |
Predicted MW | 10.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Bioactivity | Cell treatment (PMID: 28120850) |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Reference Data | |
RefSeq | NP_002610 |
Locus ID | 5196 |
Refseq Size | 878 |
Cytogenetics | 4q13.3 |
Refseq ORF | 303 |
Synonyms | CXCL4; PF-4; SCYB4 |
Summary | This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection
,Guo, L;Feng, K;Wang, YC;Mei, JJ;Ning, RT;Zheng, HW;Wang, JJ;Worthen, GS;Wang, X;Song, J;Li, QH;Liu, LD;,
Mucosal Immunol 2017
,PubMed ID 28120850
[PF4
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Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TP720045 | Recombinant protein of human platelet factor 4 (PF4) |
USD 299.00 |
|
LY400930 | Transient overexpression lysate of platelet factor 4 (PF4) |
USD 315.00 |
|
PH311322 | PF4 MS Standard C13 and N15-labeled recombinant protein (NP_002610) |
USD 1,995.00 |
|
LC400930 | PF4 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
AR50929PU-N | Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 820.00 |
|
TP723362 | Purified recombinant protein of Human platelet factor 4 (PF4). |
USD 230.00 |
|
AR50929PU-S | Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 320.00 |
USD 299.00
USD 275.00