PF4 (NM_002619) Human Recombinant Protein

CAT#: TP311322

Recombinant protein of human platelet factor 4 (PF4)

Product images

Specifications

Product Data

• Description: Recombinant protein of human platelet factor 4 (PF4)
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 10.7 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Bioactivity: Cell treatment (PMID: 28120850)
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_002610
• Locus ID: 5196
• Refseq Size: 878
• Cytogenetics: 4q13.3
• Refseq ORF: 303
• Synonyms: CXCL4; PF-4; SCYB4
• Summary: This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction