COMP (NM_000095) Human Recombinant Protein

CAT#: TP311080

Recombinant protein of human cartilage oligomeric matrix protein (COMP)

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 Product Datasheet for 'TP311080'

USD 438

USD 730


Availability*
In Stock

Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human cartilage oligomeric matrix protein (COMP)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC211080. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 80.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000086
Locus ID 1311
Refseq Size 2471
Cytogenetics 19p13.11
Refseq ORF 2271
Synonyms EDM1; EPD1; MED; PSACH; THBS5
Summary The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]
Protein Families
Protein Pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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