Serum Amyloid A (SAA1) (NM_000331) Human Recombinant Protein

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SKU
TP310664L
Recombinant protein of human serum amyloid A1 (SAA1), transcript variant 1, 1 mg
  $9,200.00
6 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC210664 protein sequence
Red=Cloning site Green=Tags(s)

MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGV
WAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 13.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000322
Locus ID 6288
UniProt ID P0DJI8
Cytogenetics 11p15.1
RefSeq Size 678
RefSeq ORF 366
Synonyms PIG4; SAA; SAA2; TP53I4
Summary This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. provided by RefSeq, Jul 2020
Protein Categories Cytokines, Secreated Proteins
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Documents
Resources

file-alt Citations

Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue
Jalkanen, Zhong, Nono Nankam et al
Cell Metab (2026) 38 (2), 419-433.e9 DOI: 10.1016/j.cmet.2025.12.008
Cited by 7
AI Summary: OriGene’s Human recombinant SAA1 protein (Cat#TP310664) was used in this study to investigate the role of SAA1 in activating immune responses in adipose-resident myeloid cells, helping to elucidate immune-metabolic interactions in colon-associated adipose tissue.
Snippet: ECL Select reagent Cytiva Cat#RPN2235 Human recombinant SAA1 protein OriGene Cat#TP310664 CD45 MicroBeads, human Miltenyi Cat#130-045-801
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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