MACROH2A1 (NM_004893) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 39.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004884 |
| Locus ID | 9555 |
| UniProt ID | O75367 |
| Cytogenetics | 5q31.1 |
| RefSeq Size | 1923 |
| RefSeq ORF | 1116 |
| Synonyms | H2A.y; H2A/y; H2AF12M; H2AFY; MACROH2A1.1; macroH2A1.2; mH2A1 |
| Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Oct 2015 |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Systemic lupus erythematosus |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MACROH2A1" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310576 | H2AFY MS Standard C13 and N15-labeled recombinant protein (NP_004884) | 10 ug |
$3,360.00
|
|
| LC417679 | Lyophilized H2AFY HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC421700 | Lyophilized H2AFY HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417679 | Transient overexpression lysate of H2A histone family, member Y (H2AFY), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY421700 | Transient overexpression lysate of H2A histone family, member Y (H2AFY), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| TP761258 | Purified recombinant protein of Human H2A histone family, member Y (H2AFY), transcript variant 4, full length, with N-terminal HIS tag, expressed in E. coli, 50ug | 50 ug |
$270.00
|
|
Citations
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