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MORC3 (NM_015358) Human Recombinant Protein

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SKU
TP310530
Recombinant protein of human MORC family CW-type zinc finger 3 (MORC3), 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
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Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC210530 protein sequence
Red=Cloning site Green=Tags(s)

MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGN
GMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKA
EHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEF
DFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSK
SLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECN
FLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELL
FRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLS
SQFENSVYKGDDDDGDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSS
RCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELR
NQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMV
SQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL
EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDL
DLQQVNYDVDVVDEILGQVVEQMSEISST

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 106.9 kDa
Concentration >0.1 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Bioactivity ELISA capture for autoantibodies (PMID: 29534337)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_056173
Locus ID 23515
UniProt ID Q14149
Cytogenetics 21q22.12
RefSeq Size 4246
RefSeq ORF 2817
Synonyms NXP2; ZCW5; ZCWCC3
Summary This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. provided by RefSeq, Feb 2016
Protein Categories Intracellular Proteins
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Other "MORC3" proteins (4)
SKU Description Size Price
PH310530 MORC3 MS Standard C13 and N15-labeled recombinant protein (NP_056173) 10 ug
$3,360.00
LC414617 Lyophilized MORC3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY414617 Transient overexpression lysate of MORC family CW-type zinc finger 3 (MORC3) (as WB positive control) 100 ug
$436.00
TP710305 Purified recombinant protein of Human MORC family CW-type zinc finger 3 (MORC3), full length, with C-terminal DDK tag, expressed in sf9, 20ug 20 ug
$540.00

file-alt Citations

Differential clinical associations of anti-nuclear matrix protein-2 autoantibodies in patients with idiopathic inflammatory myopathies
Yang, Lu, Peng et al
Arthritis & rheumatology (Hoboken, N.J.) (2018)
AI Summary: OriGene’s purified recombinant MORC3 protein was used to coat ELISA plates for detecting anti-NXP-2 autoantibody levels in patient sera, enabling the study’s investigation of disease activity associations in idiopathic inflammatory myopathies.
Snippet: described (20, 30), with some modifications. Briefly, 96-well polyvinyl plates were coated with purified recombinant protein of MORC3 (50 ng/well) (Origene Technologies, MD, USA) Page 9. Accepted Article This article is protected by copyright. All rights reserved
Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset
Tansley, Betteridge, Shaddick et al
Rheumatology (Oxford) (2014)
Cited by 170
AI Summary: OriGene's recombinant NXP2 (rNXP2) protein was used to coat ELISA plates for the detection of anti-NXP2 autoantibodies, enabling the study to assess their association with calcinosis and disease severity in juvenile dermatomyositis patients.
Snippet: ELISA. ELISA was conducted as previously described [9], with some modifications. Ninety-six-well polystyrene plates were coated with rNXP2 (Origene Technologies, Rockville, MD, USA) at 4°C for 16 h. Samples were diluted to 1:200. ... Cite SaveSaving
Oral Abstracts 3: Adolescent and Young Adult • O13. Hypermobility is a Risk Factor for Musculoskeletal Pain in Adolescence: Findings From a Prospective Cohort Study
Tobias, Deere, Palmer et al
Rheumatology (2013)
AI Summary: No OriGene products are mentioned in the provided title, abstract, or snippet, so there is no contribution from OriGene products to summarize for this paper.
Showing 1-3 of 3 papers.
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