p53R2 (RRM2B) (NM_015713) Human Recombinant Protein
SKU
TP310340
Recombinant protein of human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 40.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_056528 |
| Locus ID | 50484 |
| UniProt ID | Q7LG56 |
| Cytogenetics | 8q22.3 |
| RefSeq Size | 4932 |
| RefSeq ORF | 1053 |
| Synonyms | MTDPS8A; MTDPS8B; P53R2 |
| Summary | This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.provided by RefSeq, Feb 2010 |
| Protein Categories | Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "p53R2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310340 | RRM2B MS Standard C13 and N15-labeled recombinant protein (NP_056528) | 10 ug |
$3,360.00
|
|
| LC414401 | Lyophilized RRM2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC433055 | Lyophilized RRM2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414401 | Transient overexpression lysate of ribonucleotide reductase M2 B (TP53 inducible) (RRM2B) (as WB positive control) | 100 ug |
$436.00
|
|
| LY433055 | Transient overexpression lysate of ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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