MARCKS (NM_002356) Human Recombinant Protein
SKU
TP310277
Recombinant protein of human myristoylated alanine-rich protein kinase C substrate (MARCKS), 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 31.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Binding assay (PMID: 25863174) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002347 |
| Locus ID | 4082 |
| UniProt ID | P29966 |
| Cytogenetics | 6q21 |
| RefSeq Size | 2589 |
| RefSeq ORF | 996 |
| Synonyms | 80K-L; MACS; PKCSL; PRKCSL |
| Summary | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Fc gamma R-mediated phagocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MARCKS" proteins (1)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310277 | MARCKS MS Standard C13 and N15-labeled recombinant protein (NP_002347) | 10 ug |
$3,360.00
|
|
Citations
Identification of novel phosphatidic acid-binding proteins in the rat brain
Park, Kang, Shin et al
Neurosci. Lett. (2015) 595, 108-113 DOI: 10.1016/j.neulet.2015.04.012
Park, Kang, Shin et al
Neurosci. Lett. (2015) 595, 108-113 DOI: 10.1016/j.neulet.2015.04.012
Cited by 11
AI Summary: OriGene’s MYC-fused MARCKS recombinant protein was used in lipid-protein overlay assays to investigate and confirm protein-phospholipid interactions in the study.
Snippet: Blocked membranes were incubated for 1 h at room temperature with 0.5 μg/mL of MYC-fused MARCKS (Origene, Rockville, MD, USA) and 1 μg/mL of GST-fused GDI1, PACSIN1, BASP1, and DPYSL2 (Novus Biologicals, LLC, Littleton, Co., USA) recombinant proteins ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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