IL2 (NM_000586) Human Recombinant Protein

CAT#: TP310013

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Recombinant protein of human interleukin 2 (IL2)


 Product Datasheet for 'TP310013'

  View other "IL2" proteins (12)

USD 748.00


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In Stock

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human interleukin 2 (IL2)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 17.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000577
Locus ID 3558
Refseq Size 822
Cytogenetics 4q27
Refseq ORF 459
Synonyms IL-2; lymphokine; TCGF
Summary The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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Other Versions

Frequently bought together (2)
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