LMOD1 (NM_012134) Human Recombinant Protein
$737.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 66.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | ELISA capture for autoantibodies (PMID: 28202777) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_036266 |
| Locus ID | 25802 |
| UniProt ID | P29536 |
| Cytogenetics | 1q32.1 |
| RefSeq Size | 3967 |
| RefSeq ORF | 1800 |
| Synonyms | 1D; 64kD; D1; MMIHS3; SM-LMOD; SMLMOD |
| Summary | The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "LMOD1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH309941 | LMOD1 MS Standard C13 and N15-labeled recombinant protein (NP_036266) | 10 ug |
$3,360.00
|
|
| LC415960 | Lyophilized LMOD1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415960 | Transient overexpression lysate of leiomodin 1 (smooth muscle) (LMOD1) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus
Johnson, Tyagi, Lee et al
Sci Transl Med (2017) 9 (377) DOI: 10.1126/scitranslmed.aaf6953
Johnson, Tyagi, Lee et al
Sci Transl Med (2017) 9 (377) DOI: 10.1126/scitranslmed.aaf6953
AI Summary: OriGene’s recombinant leiomodin-1 protein was used in immunoblotting experiments to detect autoantibodies in patient samples, helping to demonstrate an autoimmune response in nodding syndrome.
Snippet: After approval by the Institutional Review Board at the NIH, adult hu- man brain homogenate extracts (temporal cortex) from patients under- going surgery for epilepsy, whole-organism lysates from O. volvulus ,or overexpressed or recombinant proteins (leiomodin-1, OriGene;DJ-1, Abcam) were resolved by SDS – polyacrylamide gel electrophoresis and analyzed by immunoblotting pooled sera (1:5000), pool...
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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