TIMP2 (NM_003255) Human Recombinant Protein

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SKU
TP309796
Recombinant protein of human TIMP metallopeptidase inhibitor 2 (TIMP2), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC209796 protein sequence
Red=Cloning site Green=Tags(s)

MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQ
YEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQ
KKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPP
KQEFLDIEDP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 21.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003246
Locus ID 7077
UniProt ID P16035
Cytogenetics 17q25.3
RefSeq Size 3670
RefSeq ORF 660
Synonyms CSC-21K; DDC8
Summary This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "TIMP2" proteins (4)
SKU Description Size Price
PH309796 TIMP2 MS Standard C13 and N15-labeled recombinant protein (NP_003246) 10 ug
$3,360.00
LC418809 Lyophilized TIMP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418809 Transient overexpression lysate of TIMP metallopeptidase inhibitor 2 (TIMP2) (as WB positive control) 100 ug
$436.00
TP720667 Purified recombinant protein of Human TIMP metallopeptidase inhibitor 2 (TIMP2) 10 ug
$340.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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