DNase II (DNASE2) (NM_001375) Human Recombinant Protein

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SKU
TP309573
Recombinant protein of human deoxyribonuclease II, lysosomal (DNASE2), 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC209573 protein sequence
Red=Cloning site Green=Tags(s)

MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRDGRALINS
PEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPAS
SAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEP
WNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIA
FPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGM
ARKPSRAYKI

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 39.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001366
Locus ID 1777
UniProt ID O00115
Cytogenetics 19p13.13
RefSeq Size 2011
RefSeq ORF 1080
Synonyms DNASE2A; DNL; DNL2
Summary This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. provided by RefSeq, Jul 2008
Protein Categories Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Lysosome
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Other "DNase II" proteins (3)
SKU Description Size Price
PH309573 DNASE2 MS Standard C13 and N15-labeled recombinant protein (NP_001366) 10 ug
$3,360.00
LC419982 Lyophilized DNASE2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419982 Transient overexpression lysate of deoxyribonuclease II, lysosomal (DNASE2) (as WB positive control) 100 ug
$436.00

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