Factor D (CFD) (NM_001928) Human Recombinant Protein

CAT#: TP309272

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Purified recombinant protein of Homo sapiens complement factor D (adipsin) (CFD)


Product Datasheet for 'TP309272'


  View other "CFD" proteins (6)

USD 399.00


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Size
    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Homo sapiens complement factor D (adipsin) (CFD)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 24.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001919
Locus ID 1675
Refseq Size 1173
Cytogenetics 19p13.3
Refseq ORF 759
Synonyms ADIPSIN; ADN; DF; PFD
Summary This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades

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Other Versions

Frequently bought together (2)
Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
    • 100 ul

USD 310.00


Rabbit polyclonal anti-CFD (Adipsin) antibody
    • 100 ug

USD 355.00

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68 Mouse Clones
HUMAN PROREINS 101