PASK (NM_015148) Human Recombinant Protein
SKU
TP309096
Recombinant protein of human PAS domain containing serine/threonine kinase (PASK), 20 µg
$867.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 142.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055963 |
| Locus ID | 23178 |
| UniProt ID | Q96RG2 |
| Cytogenetics | 2q37.3 |
| RefSeq Size | 4588 |
| RefSeq ORF | 3969 |
| Synonyms | PASKIN; STK37 |
| Summary | This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Nov 2011 |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PASK" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH309096 | PASK MS Standard C13 and N15-labeled recombinant protein (NP_055963) | 10 ug |
$3,360.00
|
|
| LC414744 | Lyophilized PASK HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414744 | Transient overexpression lysate of PAS domain containing serine/threonine kinase (PASK) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
The metabolic sensor PASK is a histone 3 kinase that also regulates H3K4 methylation by associating with H3K4 MLL2 methyltransferase complex
Karakkat, Kaimala, Sreedharan et al
Nucleic Acids Res (2019) 47 (19), 10086-10103 DOI: 10.1093/nar/gkz786
Karakkat, Kaimala, Sreedharan et al
Nucleic Acids Res (2019) 47 (19), 10086-10103 DOI: 10.1093/nar/gkz786
Cited by 19
AI Summary: In this study, OriGene products—including the PASK shRNA (OriGene, TL313863) and PASK cDNA (OriGene, RC216656)—were used to manipulate PASK expression levels in cells, enabling the authors to investigate the role of PASK in histone H3 modification and muscle cell differentiation.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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