MEF2D (NM_005920) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 55.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005911 |
| Locus ID | 4209 |
| UniProt ID | Q14814 |
| Cytogenetics | 1q22 |
| RefSeq Size | 5996 |
| RefSeq ORF | 1563 |
| Summary | This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2012 |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MEF2D" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH308748 | MEF2D MS Standard C13 and N15-labeled recombinant protein (NP_005911) | 10 ug |
$3,360.00
|
|
| LC416984 | Lyophilized MEF2D HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY416984 | Transient overexpression lysate of myocyte enhancer factor 2D (MEF2D) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Fortilin binds and stabilizes MEF2C, activates it through phosphorylation, and drives transcription of the cell structural and survival protein CTNNA3
Nakashima, Mukherjee, Pinkaew et al
Journal of Biological Chemistry (2026)
Nakashima, Mukherjee, Pinkaew et al
Journal of Biological Chemistry (2026)
AI Summary: OriGene’s recombinant human MEF2C protein was used in binding assays to investigate and confirm the direct interaction between fortilin and MEF2C, supporting the study’s findings on fortilin-mediated stabilization and activation of MEF2C.
Snippet: ide-labeled rh-fortilin with varying concentrations of MEF2C (range: 30 pM to 250 nM;OriGene,
Showing 1-1 of 1 papers.
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in shipping.
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