NOXA1 (NM_006647) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 51.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_006638 |
| Locus ID | 10811 |
| UniProt ID | Q86UR1 |
| Cytogenetics | 9q34.3 |
| RefSeq Size | 1650 |
| RefSeq ORF | 1449 |
| Synonyms | NY-CO-31; p51NOX; SDCCAG31 |
| Summary | This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2011 |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "NOXA1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH308357 | NOXA1 MS Standard C13 and N15-labeled recombinant protein (NP_006638) | 10 ug |
$3,360.00
|
|
| LC416502 | Lyophilized NOXA1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY416502 | Transient overexpression lysate of NADPH oxidase activator 1 (NOXA1) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage
Albert, Brinkmann, Pokrzywa et al
Cell death & disease (2020) 11 (9), 740 DOI: 10.1038/s41419-020-02923-x
Albert, Brinkmann, Pokrzywa et al
Cell death & disease (2020) 11 (9), 740 DOI: 10.1038/s41419-020-02923-x
Cited by 44
AI Summary: OriGene’s flag-NOXA recombinant protein was used in in vitro ubiquitylation and binding assays to investigate how CHIP regulates NOXA stability and degradation after DNA damage.
Snippet: In vitro ubiquitylation assays For in vitro ubiquitylation and binding assays recombinant proteins were purchased from Boston Biochem (ubiquitin, CHIP-6xHis, UbcH5a, UbcH5b, UBE1), Abcam (His-MCL-1), Origene (flag-NOXA), and BPS Bioscience (flag-XIAP)28. Recombinant protein NOXAwt was synthesized by Lifetein (Somerset, USA) (Sequence NOXAwt: MPGKKARKNAQPSPARAPAELEVEC ATQLRRFGDKLNFRQKLLNLISKLFCSGT)
Showing 1-1 of 1 papers.
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