Apc2 (ANAPC2) (NM_013366) Human Recombinant Protein

CAT#: TP307539

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Recombinant protein of human anaphase promoting complex subunit 2 (ANAPC2)


 Product Datasheet for 'TP307539'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human anaphase promoting complex subunit 2 (ANAPC2)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC207539. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 93.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_037498
Locus ID 29882
Refseq Size 2733
Cytogenetics 9q34.3
Refseq ORF 2466
Synonyms APC2
Summary A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101