Dynamin 1 (DNM1) (NM_001005336) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 95.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001005336 |
| Locus ID | 1759 |
| UniProt ID | Q05193 |
| Cytogenetics | 9q34.11 |
| RefSeq Size | 3253 |
| RefSeq ORF | 2553 |
| Synonyms | DEE31; DNM; EIEE31 |
| Summary | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Dynamin 1" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306284 | DNM1 MS Standard C13 and N15-labeled recombinant protein (NP_001005336) | 10 ug |
$3,360.00
|
|
| LC418003 | Lyophilized DNM1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC423862 | Lyophilized DNM1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418003 | Transient overexpression lysate of dynamin 1 (DNM1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY423862 | Transient overexpression lysate of dynamin 1 (DNM1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Barber, Goldschmidt, Ma et al
Front Synaptic Neurosci (2022) 14, 855673 DOI: 10.3389/fnsyn.2022.855673
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