Dynamin 1 (DNM1) Mouse Monoclonal Antibody [Clone ID: 3G4B6]

SKU TA336537

Mouse Monoclonal Dynamin Antibody (3G4B6)

Product Data

• Clone Name: 3G4B6
• Application: ELISA, FC, IHC, IP, Simple Western, WB
• Recommended Dilution: Immunohistochemistry-Paraffin: 1:200- 1:1000, Immunohistochemistry-Frozen: 1:200- 1:1000, ELISA: 1:10000, Immunohistochemistry: 1:10-1:500, Simple Western: 1:50, Flow Cytometry: 1 ug per million cells, Western Blot: 1:500- 1:2000, Knockout Validated, Immunoprecipitation
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human Dynamin expressed in E. coli. [UniProt# Q05193]
• Buffer: Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Purification: Ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 97 kDa
• Gene Name: dynamin 1
• Database Link:
  NP_004399
  Q05193
• Background: Dynamin (Dynamin-1, Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin (neuron-specific), Dynamin-2 (ubiquitously expressed), and Dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that Dynamin gene expression is induced during neuronal differentiation.
• Synonyms: DNM
• Note: This Dynamin (3G4B6) antibody is useful for Western Blot, Immunohistochemistry on paraffin-embedded sections and ELISA.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis