MSH2 (NM_000251) Human Recombinant Protein

CAT#: TP305848

Recombinant protein of human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2)

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 Product Datasheet for 'TP305848'

USD 438.00

USD 730.00


Availability*
In Stock

Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC205848. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 104.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000242
Locus ID 4436
Refseq Size 3145
Cytogenetics 2p21-p16.3
Refseq ORF 2802
Synonyms COCA1; FCC1; HNPCC; HNPCC1; LCFS2
Summary This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Protein Families
Protein Pathways
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