MSH2 (NM_000251) Human Recombinant Protein
SKU
TP305848
Recombinant protein of human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2), 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 104.6 kDa |
| Concentration | >200 ug/mL as determined by Microplate Bradford Protein Assay method |
| Purity | > 90% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000242 |
| Locus ID | 4436 |
| UniProt ID | P43246 |
| Cytogenetics | 2p21-p16.3 |
| RefSeq Size | 3226 |
| RefSeq ORF | 2802 |
| Synonyms | COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2 |
| Summary | This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2012 |
| Protein Categories | Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Skin, Intracellular Proteins |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Colorectal cancer, Mismatch repair, Pathways in cancer |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MSH2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305848 | MSH2 MS Standard C13 and N15-labeled recombinant protein (NP_000242) | 10 ug |
$3,360.00
|
|
| LC424843 | Lyophilized MSH2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424843 | Transient overexpression lysate of mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP762320 | Purified recombinant protein of Human mutS homolog 2, colon cancer, nonpolyposis type 1 (E.coli) (MSH2), Tyr815-Asn920, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
| TP762365 | Purified recombinant protein of Human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2), Tyr121-Ile169-GGGGS-Pro837-Lys907, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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