TJP2 (NM_004817) Human Recombinant Protein

CAT#: TP305295

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Recombinant protein of human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 1


Product Datasheet for 'TP305295'


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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 133.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_004808
Locus ID 9414
Refseq Size 4618
Cytogenetics 9q21.11
Refseq ORF 3570
Synonyms C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
Summary This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Protein Pathways Tight junction, Vibrio cholerae infection

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