CLIC2 (NM_001289) Human Recombinant Protein

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TP304727
Recombinant protein of human chloride intracellular channel 2 (CLIC2), 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC204727 protein sequence
Red=Cloning site Green=Tags(s)

MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNP
PFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLL
KEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFS
GVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQKS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 28.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Bioactivity ELISA capture for autoantibodies (PMID: 28862243)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001280
Locus ID 1193
UniProt ID O15247
Cytogenetics Xq28
RefSeq Size 2694
RefSeq ORF 741
Synonyms CLCNL2; CLIC2b; MRXS32; XAP121
Summary This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. provided by RefSeq, Jul 2017
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Ion Channels: Other
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Other "CLIC2" proteins (4)
SKU Description Size Price
PH304727 CLIC2 MS Standard C13 and N15-labeled recombinant protein (NP_001280) 10 ug
$3,360.00
LC420025 Lyophilized CLIC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY420025 Transient overexpression lysate of chloride intracellular channel 2 (CLIC2) (as WB positive control) 100 ug
$436.00
TP720238 Recombinant protein of human chloride intracellular channel 2 (CLIC2) 10 ug
$330.00

file-alt Citations

Association of anti-CLIC2 and anti-HMGB1 autoantibodies with higher disease activity in systemic lupus erythematosus patients
Syahidatulamali, Wan Syamimee, Azwany et al
J Postgrad Med (2017) 63 (4), 257-261 DOI: 10.4103/jpgm.JPGM_499_16
Snippet: CLIC2 (TP304727) and HMGB1 (TP720309) recombinant proteins were purchased from OriGene (Rockville, MD, USA)
Figure
Showing 1-1 of 1 papers.
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