Epac1 (RAPGEF3) (NM_006105) Human Recombinant Protein
SKU
TP304518
Recombinant protein of human Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3), transcript variant 2, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 99.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_006096 |
| Locus ID | 10411 |
| UniProt ID | O95398 |
| Cytogenetics | 12q13.11 |
| RefSeq Size | 5773 |
| RefSeq ORF | 2769 |
| Synonyms | bcm910; CAMP-GEFI; EPAC; EPAC1; HSU79275 |
| Summary | Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Leukocyte transendothelial migration, Long-term potentiation |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Epac1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304518 | RAPGEF3 MS Standard C13 and N15-labeled recombinant protein (NP_006096) | 10 ug |
$3,360.00
|
|
| PH319138 | RAPGEF3 MS Standard C13 and N15-labeled recombinant protein (NP_001092002) | 10 ug |
$3,360.00
|
|
| LC401841 | Lyophilized RAPGEF3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420629 | Lyophilized RAPGEF3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401841 | Transient overexpression lysate of Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420629 | Transient overexpression lysate of Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| TP319138 | Recombinant protein of human Rap guanine nucleotide exchange factor (GEF) 3 (RAPGEF3), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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