GNS (NM_002076) Human Recombinant Protein

CAT#: TP304458

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Recombinant protein of human glucosamine (N-acetyl)-6-sulfatase (GNS)


Product Datasheet for 'TP304458'


  View other "GNS" proteins (4)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human glucosamine (N-acetyl)-6-sulfatase (GNS)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC204458. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 58.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002067
Locus ID 2799
Refseq Size 5144
Cytogenetics 12q14.3
Refseq ORF 1656
Synonyms G6S
Summary The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Glycosaminoglycan degradation, Lysosome, Metabolic pathways

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