Superoxide Dismutase 3 (SOD3) (NM_003102) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 24.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003093 |
| Locus ID | 6649 |
| UniProt ID | P08294 |
| Cytogenetics | 4p15.2 |
| RefSeq Size | 1546 |
| RefSeq ORF | 720 |
| Synonyms | EC-SOD |
| Summary | This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. provided by RefSeq, Oct 2015 |
| Protein Categories | Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Superoxide Dismutase 3" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304156 | SOD3 MS Standard C13 and N15-labeled recombinant protein (NP_003093) | 10 ug |
$3,360.00
|
|
| LC418899 | Lyophilized SOD3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418899 | Transient overexpression lysate of superoxide dismutase 3, extracellular (SOD3) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease
Darci-Maher, Alvarez, Arasu et al
EBioMedicine (2023) 92, 104620 DOI: 10.1016/j.ebiom.2023.104620
Darci-Maher, Alvarez, Arasu et al
EBioMedicine (2023) 92, 104620 DOI: 10.1016/j.ebiom.2023.104620
Cited by 68
AI Summary: In this study, OriGene’s recombinant CCDC80 (Cat: TP762230) and SOD3 (Cat: TP304156) proteins were used to treat HepG2 liver cells, enabling the authors to assess the impact of these adipose-derived secreted proteins on genes related to steatosis and lipid processing in the context of obesity-related non-alcoholic fatty liver disease.
Snippet: eins and sample collection for RNA-seq experiment The HepG2 cells were seeded in a 12-well plate (1 × 105 cells/well) in 1 ml of culture medium. The next day, the cells were treated with CCDC80 (Origene;Cat: TP762230) or SOD3 (Origene;Cat: TP304156) recombinant proteins (0 and 20 ng/ml) for 24 h. Then the cells were lysed and RNA was extracted using the miRNeasy micro kit (Qiagen). Librar
Showing 1-1 of 1 papers.
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