JUNB (NM_002229) Human Recombinant Protein
$7,820.00
6 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 35.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Enzyme substrate (PMID: 29804834) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002220 |
| Locus ID | 3726 |
| UniProt ID | P17275 |
| Cytogenetics | 19p13.13 |
| RefSeq Size | 1832 |
| RefSeq ORF | 1041 |
| Synonyms | AP-1 |
| Summary | Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGACGTCA-3'.UniProtKB/Swiss-Prot Function |
| Protein Categories | Cancer: Haematopoietic and Lymphoid, Cancer: Skin, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
Nat Commun (2025) 16 (1), 4055 DOI: 10.1038/s41467-025-59109-2
Connelly, Hullin, Abdolalizadeh et al
Nat Commun (2025) 16 (1), 4055 DOI: 10.1038/s41467-025-59109-2
Cited by 2
AI Summary: OriGene products contributed to this study by providing recombinant proteins—ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), and FOS2L (TP760114)—used in functional assays to investigate gene regulatory mechanisms underlying pancreatic cancer risk.
Snippet: ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) proteins were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
Allelic effects on KLHL17 expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
medRxiv (2024)
Connelly, Hullin, Abdolalizadeh et al
medRxiv (2024)
Snippet: ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) protein were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
Activating transcription factor 3 inhibits endometrial carcinoma aggressiveness via JunB suppression
Wang, Li, Wang et al
Int. J. Oncol. (2020) 57 (3), 707-720 DOI: 10.3892/ijo.2020.5084
Wang, Li, Wang et al
Int. J. Oncol. (2020) 57 (3), 707-720 DOI: 10.3892/ijo.2020.5084
Cited by 14
AI Summary: In this study, OriGene’s His-ATF3 and JunB proteins were used to determine the binding affinity between ATF3 and JunB, supporting the investigation of ATF3’s inhibitory role in endometrial carcinoma aggressiveness.
Snippet: The dissociation rate constant (Kd) between His‑ATF3 and JunB (Origene Technologies, Inc.) was determined using BIAcore 3000 (BIAcore, Inc.) and the data were analyzed using BIAEVALUTION software version 4.1 (BIAcore, Inc.);- The dissociation rate constant (Kd) between His‑ATF3 and JunB (Origene Technologies, Inc.) was determined using BIAcore 3000 (BIAcore, Inc.) and the data were analyzed using BIAEVALUTION software version 4.1 (BIAcore, Inc.)
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
Weinert, Narita, Satpathy et al
Cell (2018) 174 (1), 231-244.e12 DOI: 10.1016/j.cell.2018.04.033
Weinert, Narita, Satpathy et al
Cell (2018) 174 (1), 231-244.e12 DOI: 10.1016/j.cell.2018.04.033
AI Summary: OriGene contributed to this study by providing five recombinant purified proteins (TTC33 [TP302360], FAM192A [TP304378], TRIM33 [TP710251], NPM1 [TP303841], and JUNB [TP303595]), which were used to investigate CBP/p300-regulated acetylation dynamics.
Snippet: … Here, we combined quantitative proteomics with CBP/p300-specific catalyti.;Five of these proteins were purchased from OriGene as recombinant purified proteins (TTC33;TP302360, FAM192A;TP304378, TRIM33;TP710251, NPM1;TP303841, JUNB;TP303595) and PPM1G was purified from yeast cells, as follows. …
Showing 1-4 of 4 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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