MAGP2 (MFAP5) (NM_003480) Human Recombinant Protein

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SKU
TP303242
Recombinant protein of human microfibrillar associated protein 5 (MFAP5), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC203242 protein sequence
Red=Cloning site Green=Tags(s)

MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTD
DLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELC
RQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 19.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003471
Locus ID 8076
UniProt ID Q13361
Cytogenetics 12p13.31
RefSeq Size 2949
RefSeq ORF 519
Synonyms AAT9; MAGP-2; MAGP2; MFAP-5; MP25
Summary This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2014
Protein Categories Cardiovascular diseases, Intracellular Proteins, Secreated Proteins
Protein Families Secreted Protein
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Other "MAGP2" proteins (3)
SKU Description Size Price
PH303242 MFAP5 MS Standard C13 and N15-labeled recombinant protein (NP_003471) 10 ug
$3,360.00
LC401177 Lyophilized MFAP5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401177 Transient overexpression lysate of microfibrillar associated protein 5 (MFAP5) (as WB positive control) 100 ug
$436.00

file-alt Citations

MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections
Barbier, Gross, Aubart et al
Am. J. Hum. Genet. (2014) 95 (6), 736-43 DOI: 10.1016/j.ajhg.2014.10.018
Cited by 145
AI Summary: OriGene’s purified recombinant human MAGP-2 protein (catalog number TP303242) was used as a control in immunoblot experiments to assess the impact of MFAP5 mutations in the study.
Snippet: Purified recombinant human MAGP-2 expressed in HEK cells (TP303242 from Origene Technologies) was used as control on each blot. Densitometric analysis was performed with Scion Image software (Scion Corporation). ... Cite SaveSaving
Showing 1-1 of 1 papers.
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