PLA2G12A (NM_030821) Human Recombinant Protein

CAT#: TP302955

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Recombinant protein of human phospholipase A2, group XIIA (PLA2G12A)


 Product Datasheet for 'TP302955'

 Cited in 1 publication.

  View other "PLA2G12A" proteins (5)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human phospholipase A2, group XIIA (PLA2G12A)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 20.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_110448
Locus ID 81579
Refseq Size 1699
Cytogenetics 4q25
Refseq ORF 567
Synonyms GXII; PLA2G12; ROSSY
Summary Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]). [supplied by OMIM, Mar 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

Citations (1)

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