SNAP29 (NM_004782) Human Recombinant Protein
$737.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 28.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004773 |
| Locus ID | 9342 |
| UniProt ID | O95721 |
| Cytogenetics | 22q11.21 |
| RefSeq Size | 4277 |
| RefSeq ORF | 774 |
| Synonyms | CEDNIK; SNAP-29 |
| Summary | This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | SNARE interactions in vesicular transport |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "SNAP29" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302179 | SNAP29 MS Standard C13 and N15-labeled recombinant protein (NP_004773) | 10 ug |
$3,360.00
|
|
| LC401502 | Lyophilized SNAP29 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401502 | Transient overexpression lysate of synaptosomal-associated protein, 29kDa (SNAP29) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Development and Validation of Diagnostic Models for Transcriptomic Signature Genes for Multiple Tissues in Osteoarthritis
Gao, Ma, Shao et al
JIR (2024) Volume 17, 5113-5127 DOI: 10.2147/JIR.S472118
Gao, Ma, Shao et al
JIR (2024) Volume 17, 5113-5127 DOI: 10.2147/JIR.S472118
AI Summary: OriGene's DAB (ZLI-9018) was utilized in this study for chromogenic detection during immunohistochemical analysis to visualize transcriptomic signature genes in multiple tissues affected by osteoarthritis.
Snippet: ections were subsequently blocked with goat serum (AR1009;Boster). Primary and secondary antibodies were then incubated sequentially. DAB (ZLI-9018, Origene) was used for chromogenic detection, and hematoxylin (G1004, Servicebio) was used for nuclear staining
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration
Hartmann, Bajaj, Otten et al
Nat Commun (2024) 15 (1), 2635 DOI: 10.1038/s41467-024-46953-x
Hartmann, Bajaj, Otten et al
Nat Commun (2024) 15 (1), 2635 DOI: 10.1038/s41467-024-46953-x
Cited by 33
AI Summary: OriGene products—specifically Syntaxin3-DDK (TP300658), SNAP29-DDK (TP302179), Syntaxin4 (TP300347), SNAP23-DDK (TP301596), and SEC22B-HIS (AR50533PU-S)—were used as purified recombinant proteins in binding assays to investigate the molecular mechanisms underlying secretory autophagy in neuroinflammation-mediated neurodegeneration.
Snippet: o bovine serum albumin (BSA)- blocked anti-His or anti-Flag-conjugated protein G Dynabeads (Invitrogen, 100-03D, HIS Cell Signaling Technology, #12698, FLAG M2, Sigma, F3165). Purified Syntaxin3-DDK (Origene, TP300658), SNAP29-DDK (Origene, TP302179), Syntaxin4 (Origene, TP300347), SNAP23-DDK (Origene, TP301596) or correspondingly SEC22B-HIS (Origene, AR50533PU-S) (100 ng) was used for the bindi
Regulation of Autophagic Flux by the 20S Proteasome
Njomen, Tepe
Cell Chem Biol (2019) 26 (9), 1283-1294.e5 DOI: 10.1016/j.chembiol.2019.07.002
Njomen, Tepe
Cell Chem Biol (2019) 26 (9), 1283-1294.e5 DOI: 10.1016/j.chembiol.2019.07.002
AI Summary: OriGene's recombinant human SNAP29 with c-Myc tag (Cat# TP302179) was used in this study to investigate the role of SNAP29 in 20S proteasome-mediated regulation of autophagosome-lysosome fusion.
Snippet: Skip to article;Recombinant human SNAP29 with c-Myc tag Origene Cat# TP302179 LysoTracker red ThermoFisher Scientific Cat# L7528 TRIzol Reagent ThermoFisher Scientific Cat# 15596026 Pierce Protein A/G Magnetic Beads ThermoFisher Scientific Cat# 88802 TURBO DNase-free kit ThermoFisher Scientific Cat# AM1907
The Discovery and Characterization of Small Molecule 20s Proteasome Activators: Implications in Proteostasis Disorders
Njomen
Thesis (2019)
Njomen
Thesis (2019)
Snippet: Reagent or Resources Source Catalogue number Human 20S proteasomes BostonBiochem E-360 20S Immunoproteasome BostonBiochem E-370 26S Proteasome BostonBiochem E-365 19S Proteasome BostonBiochem E-366 Proteasome 20S (Saccharomyces cerevisiae) Enzo Life Sciences BML-PW8775 Recombinant human SNAP29 with c-Myc tag Origene TP302179 Human tau441 full length protein Abcam ab84700 Human a-synuclein full length protein Abcam ab51189 Recombinant human GAPDH protein Abcam ab77109 Lysozyme ThermoFisher Scientific 89833
Showing 1-4 of 4 papers.
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