AlaRS (AARS) (NM_001605) Human Recombinant Protein

CAT#: TP302136

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Recombinant protein of human alanyl-tRNA synthetase (AARS)


 Product Datasheet for 'TP302136'

  View other "AARS" proteins (3)

USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human alanyl-tRNA synthetase (AARS)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 106.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001596
Locus ID 16
Refseq Size 3344
Cytogenetics 16q22.1
Refseq ORF 2904
Synonyms CMT2N; EIEE29
Summary The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]
Protein Pathways Aminoacyl-tRNA biosynthesis

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