AlaRS (AARS) (NM_001605) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 106.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001596 |
| Locus ID | 16 |
| UniProt ID | P49588 |
| Cytogenetics | 16q22.1 |
| RefSeq Size | 3344 |
| RefSeq ORF | 2904 |
| Synonyms | AARS; CMT2N; DEE29; EIEE29 |
| Summary | The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. provided by RefSeq, Jul 2008 |
| Protein Categories | Enzyme: Ligase, Intracellular Proteins, Nervous system: Neurodegenerative diseases |
| Protein Pathways | Aminoacyl-tRNA biosynthesis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "AlaRS" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302136 | AARS MS Standard C13 and N15-labeled recombinant protein (NP_001596) | 10 ug |
$3,360.00
|
|
| LC400604 | Lyophilized AARS HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400604 | Transient overexpression lysate of alanyl-tRNA synthetase (AARS) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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