GPBB (PYGB) (NM_002862) Human Recombinant Protein

CAT#: TP302077

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Recombinant protein of human phosphorylase, glycogen; brain (PYGB)


 Product Datasheet for 'TP302077'

  View other "PYGB" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human phosphorylase, glycogen; brain (PYGB)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 96.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002853
Locus ID 5834
Refseq Size 4131
Cytogenetics 20p11.21
Refseq ORF 2529
Synonyms GPBB
Summary The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Insulin signaling pathway, Starch and sucrose metabolism

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