PPP2R5D (NM_006245) Human Recombinant Protein
SKU
TP301945
Purified recombinant protein of Homo sapiens protein phosphatase 2, regulatory subunit B', delta isoform (PPP2R5D), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 69.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_006236 |
| Locus ID | 5528 |
| UniProt ID | Q14738 |
| Cytogenetics | 6p21.1 |
| RefSeq Size | 3065 |
| RefSeq ORF | 1806 |
| Synonyms | B56D; B56delta; MRD35 |
| Summary | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Phosphatase |
| Protein Pathways | Oocyte meiosis, Wnt signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PPP2R5D" proteins (10)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300647 | PPP2R5D MS Standard C13 and N15-labeled recombinant protein (NP_851307) | 10 ug |
$3,360.00
|
|
| PH301945 | PPP2R5D MS Standard C13 and N15-labeled recombinant protein (NP_006236) | 10 ug |
$3,360.00
|
|
| LC405833 | Lyophilized PPP2R5D HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC405834 | Lyophilized PPP2R5D HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC416775 | Lyophilized PPP2R5D HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY405833 | Transient overexpression lysate of protein phosphatase 2, regulatory subunit B', delta isoform (PPP2R5D), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY405834 | Transient overexpression lysate of protein phosphatase 2, regulatory subunit B', delta isoform (PPP2R5D), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY416775 | Transient overexpression lysate of protein phosphatase 2, regulatory subunit B', delta isoform (PPP2R5D), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300647 | Recombinant protein of human protein phosphatase 2, regulatory subunit B', delta isoform (PPP2R5D), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP760026 | Recombinant protein of human protein phosphatase 2, regulatory subunit B', delta (PPP2R5D), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
Citations
Dysregulation of PP2A-Akt interaction contributes to Sucrose non-fermenting related kinase (SNRK) deficiency induced insulin resistance in adipose tissue
Li, An, Lai et al
Mol Metab (2019) 28, 26-35 DOI: 10.1016/j.molmet.2019.07.009
Li, An, Lai et al
Mol Metab (2019) 28, 26-35 DOI: 10.1016/j.molmet.2019.07.009
Cited by 22
AI Summary: In this study, OriGene products—specifically the human recombinant SNRK protein (Cat# TP304395) and human recombinant PPP2R5D protein (Cat# TP312326)—were used in in vitro phosphorylation assays to demonstrate that SNRK directly phosphorylates PPP2R5D, elucidating a key mechanism by which SNRK regulates insulin signaling in adipose tissue.
Showing 1-1 of 1 papers.
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