MRPL28 (NM_006428) Human Recombinant Protein
Recombinant protein of human mitochondrial ribosomal protein L28 (MRPL28), nuclear gene encoding mitochondrial protein
Product Datasheet for 'TP301794'
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|Description||Recombinant protein of human mitochondrial ribosomal protein L28 (MRPL28), nuclear gene encoding mitochondrial protein|
|Expression cDNA Clone or AA Sequence||Recombinant protein was produced with TrueORF clone, RC201794. Click on the TrueORF clone link to view cDNA and protein sequences.|
|Predicted MW||30 kDa|
|Concentration||>50 ug/mL as determined by microplate BCA method|
|Purity||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Buffer||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.|
|Summary||Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008].|