PEX19 (NM_002857) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 32.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002848 |
| Locus ID | 5824 |
| UniProt ID | P40855 |
| Cytogenetics | 1q23.2 |
| RefSeq Size | 3722 |
| RefSeq ORF | 897 |
| Synonyms | D1S2223E; HK33; PBD12A; PMP1; PMPI; PXF; PXMP1 |
| Summary | This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2010 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "PEX19" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301756 | PEX19 MS Standard C13 and N15-labeled recombinant protein (NP_002848) | 10 ug |
$3,360.00
|
|
| LC419085 | Lyophilized PEX19 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419085 | Transient overexpression lysate of peroxisomal biogenesis factor 19 (PEX19), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP325241 | Purified recombinant protein of Homo sapiens peroxisomal biogenesis factor 19 (PEX19), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
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