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PCNA (NM_002592) Human Recombinant Protein

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SKU
TP301741
Recombinant protein of human proliferating cell nuclear antigen (PCNA), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC201741 protein sequence
Red=Cloning site Green=Tags(s)

MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGV
NLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMP
SGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALR
YLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 28.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002583
Locus ID 5111
UniProt ID P12004
Cytogenetics 20p12.3
RefSeq Size 1355
RefSeq ORF 783
Synonyms ATLD2
Summary The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair
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Other "PCNA" proteins (9)
SKU Description Size Price
PH301741 PCNA MS Standard C13 and N15-labeled recombinant protein (NP_002583) 10 ug
$3,360.00
LC400929 Lyophilized PCNA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405433 Lyophilized PCNA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC430596 Lyophilized PCNA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400929 Transient overexpression lysate of proliferating cell nuclear antigen (PCNA), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY405433 Transient overexpression lysate of proliferating cell nuclear antigen (PCNA), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY430596 Transient overexpression lysate of proliferating cell nuclear antigen (PCNA), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP750150 Purified recombinant protein of Human proliferating cell nuclear antigen (PCNA), transcript variant 2, full length, tag free, expressed in E.Coli, 50 ug 50 ug
$270.00
TP760481 Purified recombinant protein of Human proliferating cell nuclear antigen (PCNA), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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