GBA (NM_001005741) Human Recombinant Protein

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SKU
TP301614
Purified recombinant protein of Homo sapiens glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 2, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC201614 protein sequence
Red=Cloning site Green=Tags(s)

MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTF
PALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQ
NLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRP
VSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLL
SGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVH
WYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDW
NLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMH
PDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 55.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001005741
Locus ID 2629
UniProt ID P04062
Cytogenetics 1q22
RefSeq Size 2583
RefSeq ORF 1608
Synonyms GBA1; GCB; GLUC
Summary This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2010
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
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Other "GBA" proteins (16)
SKU Description Size Price
PH301614 GBA MS Standard C13 and N15-labeled recombinant protein (NP_001005741) 10 ug
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PH312242 GBA MS Standard C13 and N15-labeled recombinant protein (NP_001005742) 10 ug
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PH316061 GBA MS Standard C13 and N15-labeled recombinant protein (NP_000148) 10 ug
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LC400055 Lyophilized GBA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423641 Lyophilized GBA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423642 Lyophilized GBA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC425145 Lyophilized GBA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC433165 Lyophilized GBA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400055 Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423641 Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY423642 Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY425145 Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY433165 Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 5 (as WB positive control) 100 ug
$436.00
TP312242 Purified recombinant protein of Homo sapiens glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 3, 20 µg 20 ug
$867.00
TP316061 Recombinant protein of human glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 1, 20 µg 20 ug
$867.00
TP761812 Purified recombinant protein of Human glucosidase, beta, acid (GBA), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 50 ug
$270.00

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