Argininosuccinate Lyase (ASL) (NM_001024943) Human Recombinant Protein

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SKU
TP301568
Recombinant protein of human argininosuccinate lyase (ASL), transcript variant 1, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC201568 protein sequence
Red=Cloning site Green=Tags(s)

MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKV
AEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELI
RTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLG
VDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTG
SSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVI
STLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLF
SGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA

SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 51.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001020114
Locus ID 435
UniProt ID P04424
Cytogenetics 7q11.21
RefSeq Size 2061
RefSeq ORF 1392
Synonyms ASAL
Summary This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Pathways Alanine, Arginine and proline metabolism, aspartate and glutamate metabolism, Metabolic pathways
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Other "Argininosuccinate Lyase" proteins (11)
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LC422562 Lyophilized ASL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC422563 Lyophilized ASL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC422564 Lyophilized ASL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC424953 Lyophilized ASL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY422562 Transient overexpression lysate of argininosuccinate lyase (ASL), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY422563 Transient overexpression lysate of argininosuccinate lyase (ASL), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY422564 Transient overexpression lysate of argininosuccinate lyase (ASL), transcript variant 4 (as WB positive control) 100 ug
$665.00
LY424953 Transient overexpression lysate of argininosuccinate lyase (ASL), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP317527 Recombinant protein of human argininosuccinate lyase (ASL), transcript variant 2, 20 µg 20 ug
$867.00

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